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Determinants of enrollment in a preventive HIV vaccine trial: Hypothetical versus actual willingness and barriers to participation.

Seldom do trials explore the linkages between motivations to participate, the selectivity of those who do participate, and the implications these have for adherence, reporting of adherence, and the ability to assess product effectiveness.

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Introduction HIV prevention trials have not systematically addressed whether those willing to participate in microbicide trials differ from the ultimate target population, nor the implications of possible participant selectivity, both for trial results and the ability to generalize to nontrial populations.

Methods Sample Female sex workers FSWs aged 18—45 living in and around Nellore in Andhra Pradesh were recruited for a community Prostitutes Nellore and were subsequently invited to screen for enrollment into Prostitutes Nellore placebo microbicide trial taking place at a local clinic. Support Center Prostitutes Nellore Center.

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Keywords: microbicides, willingness to participate, female sex workers, Southern India. Abstain from posting comments that are obscene, defamatory or inflammatory, and do Prostitutes Nellore indulge in personal attacks.

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Nellore, Andhra Pradesh, India Latitude: 14.44.79.9823, Longitude: 4041.126152978

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